SARS-CoV-2 (COVID19) yana tashe a duniya, kuma ana sanin allurar rigakafi a matsayin hanya mafi tattalin arziki da inganci don shawo kan cutar ta kwayar cutar.Ƙimar rigakafin al'ada ta al'ada galibi tana amfani da hanyoyin gano ƙwayoyin cuta don tantance tasirin alluran ta hanyar gwaje-gwajen kawar da kai;
Hanyoyin al'ada suna ɗaukar lokaci kuma suna da ƙarancin inganci, yawanci suna ɗaukar kwanaki 2 zuwa 4 don kammala kimantawa, kuma saboda yawancinsu suna amfani da ƙwayoyin cuta masu rai, yana buƙatar aiwatar da shi a cikin matakin biosafety 3 ko sama da dakin gwaje-gwaje, wanda shine lokaci- cinyewa da wahala, kuma yana kawo rashin jin daɗiga kimantawa na fadadawa da tarawa.Sabili da haka, akwai buƙatar gaggawa don hanya mai sauƙi da sauri wanda ya dace da kimantawa na rigakafi masu kariya a cikin yawan jama'a.
Ana amfani da Aehealth COVID19 Neutralisation Kits Test Kits don gano ƙwayoyin rigakafin COVID19 a cikin jini, plasma ko duka jini.Ana iya amfani dashi don saurin ganowa a cikin vitro.na asibiti da aka yi amfani da su a cikin kimantawa na ƙarin tasirin maganin COVID19 da kuma kimanta ƙwayoyin rigakafi a cikin marasa lafiya da aka murmure bayan kamuwa da cuta.
Sauƙi aiki
- Babu buƙatar ƙwararru don horar da su
- Mai jituwa tare da nau'in samfuri da yawa: Serum/Plasma/Jini gabaɗaya/jinin yatsa.
Dace
- Babu kayan aiki da ake buƙata
Mai inganci
- Gwaji: 15-20 mins;
Kwayoyin rigakafin hana kamuwa da cuta suna dakatar da kamuwa da cuta da kyau ta hanyar toshe hulɗar tsakanin kwayar cutar ta COVID19 da sel masu masaukin baki.Yawancin ƙwayoyin rigakafi na neutralization suna amsawa ga yanki mai ɗaure mai karɓa (RBD) na furotin mai karu, wanda ke ɗaure kai tsaye ga mai karɓar saman tantanin halitta ACE2.antibodies-online a halin yanzu yana ba da ƙwayoyin rigakafi guda biyu dangane da clone CR3022.Yayin da yawancin S-protein RBD masu ɗaure ƙwayoyin rigakafi suna gasa don haɗin antigen tare da ACE2, CR3022 epitope ba ya haɗuwa da rukunin ACE2-dauri.
Don haka baya hana daurin antibodies neutralization.Yayin da CR3022 da kanta ke ba da sakamako mai rauni kawai, an nuna shi don yin aiki tare da sauran S-protein RBD masu ɗaure ƙwayoyin rigakafi don kawar da COVID19.
