Yankin Spike glycoprotein receptor-binding (RBD) na SARS-CoV-2 yana daidaita haɗin ƙwayar ƙwayar cuta zuwa mai karɓar enzyme 2 (ACE2) mai jujjuyawar angiotensin akan saman sel ɗan adam.Don haka, hulɗar Spike-ACE2 shine muhimmin mahimmancin ƙayyadaddun abu don kamuwa da cuta ta hoto ko bidiyo mai zagaya yanar gizo da sauri.Wani sabon rukunin phylogenetic na SARS-CoV-2 (jinin B.1.1.7), wanda ke fasalin maye gurbin amino acid a cikin Spike RBD (N501Y maye gurbin).
Dangane da sabon binciken da Ma'aikatar Lafiya ta Burtaniya ta yi, dangane da bayanan jeri na kwayoyin halitta, cututtukan cututtukan fata da yin samfuri, kamuwa da cutar bambance-bambancen nau'in SARS-CoV-2 ya kusan 40-70% sama da sauran masanin kimiyyar gyara da aka gano. .Amsa da sauri da ganowa ɗaya ne daga cikin ma'auni mai mahimmanci na rigakafi da sarrafawa.
Ana amfani da kit ɗin don in vitro qualitative gano kwayoyin halittar ORF1ab/N/S na novel coronavirus 2019-nCoV a cikin samfuran numfashi, da yin buga maye akan N501Y lokaci guda.
Kit ɗin yana ɗaukar hanyar ARMS, yana ɗaukar S gene of novel coronavirus (2019-nCoV) a matsayin yankin da aka yi niyya don buga maye gurbi, yana ƙirƙira ƙayyadaddun ƙayyadaddun abubuwan ƙira da bincike akan N501Y.
| Kayayyaki | Takaddun bayanai | Adana zafin jiki | Bayani |
| Kit ɗin PCR na Real Time don NovelCoronavirus 2019-nCoV daNovel Coronavirus 2019-nCoVHalin Halitta (N501Y) | 48T | -20 ℃ | Analytes: Nau'in daji na N501Y,Nau'in Mutant na N501Y, ORF1ab,N gene da Internal control |
Dacewar Samfura
- Oropharyngeal Swabs
- Nasopharyngeal Swab
- Ruwan Lavage Bronchoalveolar
- Sputum
Abubuwan Kit
- RT-PCR amsa buffer
- RT-PCR enzyme mix
- Nau'in daji tabbatacce iko
- Canjin ingantaccen iko
- Sarrafa mara kyau
Nau'in maye gurbin N501Y
